Natinuel BIO-DERM AHAs 16% GHK-CU is a rich, full-bodied cream formulated as a modern scientific solution for achieving skin with a biological age significantly younger than its chronological age. This product is specifically designed for mature skin and is part of the “Bio Line.”
BIO-DERM’s unique formulation is designed to ensure high dermatological efficacy by creating a powerful biochemical synergy. It promotes multi-level restructuring and regeneration within skin tissue by combining a high concentration of Amphoteric Alpha Hydroxy Acids (AHAs) (16%) for cellular renewal with a specialized Copper Peptide Complex (implied by GHK-CU) for dermal matrix stimulation. This foundational approach delivers significant bio-functional rejuvenation, enhancing tone, elasticity, and reducing the appearance of various types of wrinkles.
The amphoteric system allows for the use of this high concentration of AHAs even on sensitive mature skin, significantly reducing common irritation (tingling/burning).
Benefits of BIO-DERM AHAs 16% GHK-CU
- Deep Dermal Stimulation: The special peptide (GHK-CU) stimulates the production of vital dermal components, including collagen, elastin, GAGs, and proteoglycans, leading to enhanced tone and elasticity
- Advanced Renewal: The 16% Amphoteric AHAs and Mandelic Acid enhance cellular turnover, reduce fine lines and wrinkles, and provide an immediate radiant, more even complexion
- Anti-Glycation & Anti-Inflammation: The peptide complex actively counteracts the glycation of proteins (a primary cause of aging stiffening) and combats skin inflammation
- Cellular Protection: Protects cellular structures against free radical damage, boosts the endogenous antioxidant system, and activates energy mechanisms for revitalized metabolic processes
- Optimal Hydration & Barrier: Sericine maintains deep epidermal hydration, regulates Transepidermal Water Loss (TEWL), and strengthens the skin barrier against external agents
BIO-DERM AHAs 16% GHK-CU Specifications
- Product Type: Stimulating, Regenerating Cream
- Capacity: 50 ml
- Texture: Full-bodied cream structure
- Application: Apply morning and evening to a cleansed face and neck. Massage gently until fully absorbed (External use only)
- Target Audience: Mature skin
- AHA Concentration: 16% (Amphoteric AHAs + Mandelic Acid)
Key active ingredients
Alpha Hydroxy Acids: AMPHOTERIC AHAs (16%)
Promotes controlled cellular turnover and hydration; allows high concentration use with reduced irritation (less tingling/burning).
Cell Remodulator: MANDELIC ACID
Epidermal cellular remodulator; provides sanitizing, firming, and brightening effects for an even, radiant complexion.
Copper Peptide Complex: PEPTIDE (GHK-CU)
Increases biosynthesis of collagen/elastin/GAGs; improves self-repair mechanisms, counteracts glycation, regulates MMPs, and combats inflammation.
Hydration & Barrier: SERICINE
Hydrates the epidermis, regulates TEWL, enhances resistance to external agents, strengthens the skin barrier, and has anti-elastase properties.
UV Protection: SUNSCREENS
Complex of UVA-UVB filters providing moderate protection.
Perfect For:
- Individuals with mature skin seeking a powerful daily treatment for visible signs of aging
- Targeting deep wrinkles, loss of tone, and reduced elasticity
- Those who need multi-level bio-functional rejuvenation in both the dermis and epidermis
- Use as a primary cream to accelerate cell turnover and regenerate the Extracellular Matrix for a biologically younger appearance
Explore the full Natinuel collection: nicheskinscent.com/categories/beauty-products/categories/natinuel




